洪 泂
 | 姓 名: | 洪泂 |
地 址: | 安徽省合肥市中国科学技术大学生命科学学院440C | |
邮 编: | 230027 | |
电 话: | (0551)-63600705 | |
电 邮: | hjiong@ustc.edu.cn | |
主 页: | http://synbio.ustc.edu.cn/ |
| 教育与科研经历 |
2008.4 - 现在 | 中国科学技术大学生命科学学院 |
2006.8 - 2008.2 | 美国弗吉尼亚理工大学，博士后 |
2003.11 - 2006.8 | 日本京都大学，博士后 |
1999.10 - 2003.2 | 日本京都大学， 博士 |
1996.7 - 2003.10 | 北京师范大学，助教/讲师 |
1993.9 - 1996.7 | 北京师范大学，硕士 |
1989.9 - 1993.7 | 安徽师范大学，本科 |
| 目前研究方向 |
1. | 以耐热酵母为平台构建利用木质纤维素生物质的微生物细胞工厂。通过合成生物学手段对耐热的马克斯克鲁维酵母进行改造，实现利用秸秆、玉米芯等材料进行乙醇、木糖醇、乳酸等产品的生产。 |
2. | 高通量DNA合成技术。高通量DNA合成技术是合成生物学中重要的使能技术，目前研究专注于研发高效去除合成过程中错误的技术。 |
| 代表性论文 |
1. | Hua Yan, Wang Jichao, Zhu Yelin, Zhang Biao, Kong Xin, Li Wenjie, Wang Dongmei, Hong Jiong*, (2019). Release of glucose repression on xylose utilization in Kluyveromyces marxianus to enhance glucose-xylose co-utilization and xylitol production from corncob hydrolysate. Microbial Cell Factories. 18：24. |
2. | Kong Xin, Zhang Biao, Hua Yan, Zhu Yelin, Li Wenjie, Wang Dongmei, Hong Jiong*, (2019). Efficient L-lactic acid production from corncob residue using metabolically engineered thermo-tolerant yeast. Bioresource Technology. 273， p220-230. |
3. | Zhang Biao, Zhu Yelin, Zhang Jia, Wang Dongmei, Sun Lianhong, Hong Jiong* , (2017). Engineered Kluyveromyces marxianus for pyruvate production at elevated temperature with simultaneous consumption of xylose and glucose. Bioresoure Technology, 224, 553-562. |
4. | Zhang Biao, Zhang Jia, Wang Dongmei, Han Ruixiang., Ding Rui, Gao Xiaolian., Sun Lianhong, Hong Jiong*, (2016). Simultaneous fermentation of glucose and xylose at elevated temperatures co-produces ethanol and xylitol through overexpression of a xylose-specific transporter in engineered Kluyveromyces marxianus. Bioresource Technology, 216, 227-237. （Best article in this issue) |
5. | Zhang Jia, Zhang Biao, Wang Dongmei, Gao Xiaolian, Sun Lianhong and Hong Jiong*, (2015). Rapid ethanol production at elevated temperatures by engineered thermotolerant Kluyveromyces marxianus via the NADP(H)-preferring xylose reductase-xylitol dehydrogenase pathway. Metabolic Engineering, 31, 140-152. |
6. | Zhang Jia, Zhang Biao, Wang Dongmei, Gao Xiaolian and Hong Jiong*, (2015). Improving xylitol production at elevated temperature with engineered Kluyveromyces marxianus through over-expressing transporters. Bioresource Technology 175: 642-645. |
7. | Wan, Wen; Li, Lulu; Xu, Qianqian; Wang, Zhefan; Yao, Yuan; Wang, Rongliang; Zhang, Jia; Liu, Haiyan; Gao, Xiaolian*; Hong, Jiong* (2014). Error removal in microchip-synthesized DNA using immobilized MutS. Nucleic Acids Research, 42(12), e102. |
8. | Zhang Jia, Zhang Biao, Wang Dongmei, Gao Xiaolian, Hong Jiong* (2014). Xylitol production at high temperature by engineered Kluyveromyces marxianus. Bioresource Technology 152:192-201. |
