江永亮


/uploads/image/2019/03/06/54b4c5d0d02201d32eb10d9269343f07.jpg 姓  名: 江永亮
 地  址: 中国科学技术大学生命科学学院
 电  话:0551-63600407
 电  邮:jyl@ustc.edu.cn
 主  页:http://czlab.ustc.edu.cn/




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 教育与科研经历
  2003.09-2007.07合肥工业大学,本科
  2007.09-2012.06

中国科学技术大学,博士

  2012.06-2014.06中国科学技术大学,博士后
  2014.06-2018.03中国科学技术大学,特任副研究员
  2018.04-中国科学技术大学,副教授


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 目前研究方向
  1.利用冷冻电镜和X-射线晶体学方法研究生物大分子的结构和功能
  2.利用结构生物学手段研究蓝细菌碳氮代谢协同调控的分子机理


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 代表性论文
  1.Jiang YL#, Wang XP#, Sun H#, Han SJ, Li WF, Cui N, Li GM, Zhang JY, Cheng W, Cao DD, Zhang ZY, Zhang CC*, Chen Y*, Zhou CZ*. Coordinating carbon and nitrogen metabolic signaling through the cyanobacterial global repressor NdhR. Proceedings of the National Academy of Sciences USA. 2018; 115(2):403-408.
  2.Yang HB#, Hou WT#, Cheng MT#, Jiang YL*, Chen Y*, Zhou CZ*. Structure of a MacAB-like efflux pump from Streptococcus pneumoniae. Nature Communications. 2018; 9(1):196.
  3.Jiang YL#, Jin H#, Yang HB, Zhao RL, Wang SL, Chen Y*, Zhou CZ*. Defining the enzymatic pathway for polymorphic O-glycosylation of the pneumococcal serine-rich repeat protein PsrP. Journal of Biological Chemistry. 2017; 292(15):6213-6224.
  4.Yang YH#, Jiang YL#, Zhang J, Wang L, Bai XH, Zhang SJ, Ren YM, Li N, Zhang YH, Zhang Z, Gong Q, Mei Y, Xue T, Zhang JR, Chen Y*, Zhou CZ*. Structural insights into SraP-mediatedStaphylococcus aureusadhesion to host cells.PLoS Pathogens. 2014; 10(6): e1004169.
  5.Shi WW#, Jiang YL#, Zhu F, Yang YH, Shao QY, Yang HB, Ren YM, Wu H*, Chen Y*, Zhou CZ*. Structure of a novel O-GlcNAc transferase GtfA reveals insights into the glycosylation of pneumococcal serine-rich repeat adhesins. Journal of Biological Chemistry. 2014; 289(30): 20898-907.
  6.Jiang YL#, Yu WL#, Zhang JW, Frolet C, Di Guilmi AM, Zhou CZ, Vernet T*, Chen Y*. Structural basis for the substrate specificity of a novel β-N-acetyl-hexosaminidase StrH protein from Streptococcus pneumoniae R6. Journal of Biological Chemistry. 2011; 286(50): 43004-12.
  7.Jiang YL#, Zhang JW#, Yu WL, Cheng W, Zhang CC, Frolet C, Di Guilmi AM, Vernet T, Zhou CZ*, Chen Y*. Structural and enzymatic characterization of theStreptococcalATP/Diadenosine polyphosphate and phosphodiester hydrolase Spr1479/SapH. Journal of Biological Chemistry. 2011; 286(41): 35906-14.


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