![]() | Name: | Hu Bing (胡兵) |
Address: | School of life science, | |
University of Science and Technology of China, Hefei, Anhui 230027, P. R. China | ||
Tel: | 86-551-63602489 | |
E-mail: | bhu@ustc.edu.cn | |
Webpage: | http://222.195.69.43/hub/ |
EDUCATION AND RESEARCH EXPERIENCE |
1984 – 1989 | Bachelor of Biophysics, University of Science and Technology of China |
1989 – 1992 | Master of Biophysics, University of Science and Technology of China |
1993 – 1998 | Ph.D. of Neurobiology, University of Hong Kong and Institute of Physiology, Chinese Academy of Sciences, Shanghai, China (joint training) |
1996 – 1999 | Lecturer, Department of Neurobiology and Biophysics, USTC, China |
2000.01 – 2001 | Associate Professor, Department of Neurobiology and Biophysics, School of Life Sciences, USTC, China |
2002 – 2004 | Postdoctoral fellow, University of California at LA, CA,University of California at Irvine, CA |
2005 – 2007.08 | Senior RA, Research Officer, Department of Anatomy, Faculty of Medicine, University of Hong Kong, Hong Kong, China |
2007.11 – present | Professor, Department of Neurobiology and Biophysics, School of Life Sciences, USTC, China |
CURRENT RESEARCH PROJECTS |
1. | To study the oligodendrocyte development, myelin formation as well as remyelination after demyelination. Currently, we are focusing on elucidation of the mechanisms underlying zebrafish CNS remyelination after injury. |
2. | To study the synapse dynamic change using in vivo time-lapse confocal microscopy imaging in zebrafish and xenopus tadpoles. |
REPRESENTATIVE PUBLICATIONS |
1. | Bing Hu, Henry K. Yip and Kwok-Fai So (1998) Localization of p75 neurotrophin receptor in the retina of the adult SD rat: An immunocytochemical study at light and electron microscopic levels. Glia 24:187-197. |
2. | Bing Hu, Angeliki Maria Nikolakopoulou and Susana Cohen-Cory (2005) BDNF stabilizes synapses and maintains the structural complexity of optic axons in vivo. Development. 132:4285-4298. |
3. | Sha Mi*, Bing Hu*, Kyungmin Hahm, Yi Luo, Edward Sai Kam Hui, Qiuju Yuan, Wai Man Wong, Li Wang, Huanxing Su, Tak-Ho Chu, Jiasong Guo, Wenming Zhang, Kwok-Fai So, Blake Pepinsky, Zhaohui Shao, Christilyn Graff, Ellen Garber, Vincent Jung, Ed Xuekui Wu & Wutian Wu* (2007) LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis. Nature Medicine. 13(10):1228-1233. (* these authors contributed equally to this work). Cover page of the issue “the LINGO of remyelination”. |
4. | Meng-Hua Xiong,†,‡ Ya-Juan Li,§,‡ Yan Bao,§ Xian-Zhu Yang,§ Bing Hu*,§ and Jun Wang*,§ (2012) Bacteria-Responsive Multifunctional Nanogel for Targeted Antibiotic Delivery. Advanced Materials. 24, 6175–6180 |
5. | Yin, W., Hu, B*. (2014) Knockdown of Lingo1b protein promotes myelination and oligodendrocyte differentiation in zebrafish. Exp. Neurol. 251:72-83. http://dx.doi.org/10.1016/j.expneurol.2013.11.012 |
6. | Da-long Ren1, Ya-juan Li1, Bing-bing Hu1, Han Wang* 2, 3 and Bing Hu*1 (2015) Melatonin regulates the rhythmic migration of neutrophils in live zebrafish. J Pineal Res., Doi:10.1111/jpi.12230. |
7. | Da-Long Ren, Ai-Ai Sun, Ya-Juan Li, Min Chen, Shu-Chao Ge and Bing Hu* (2015) Exogenous melatonin inhibits neutrophil migration through suppression of ERK activation. Journal of Endocrinology. 227 :49–60. |
8. | Tian C, Zou S, Hu B* (2016) Extraocular Source of Oligodendrocytes Contribute to Retinal Myelination and Optokinetic Responses in Zebrafish. Invest Ophthalmol Vis Sci. 2016 Apr 1;57(4):2129-38. doi: 10.1167/iovs.15-17675. (highlight in the same issue) |
9. | Chen, M., Xu, Y., Huang, R., Huang Yubin, Ge Shuchao and Hu Bing* (2016) N-Cadherin is Involved in Neuronal Activity-Dependent Regulation of Myelinating Capacity of Zebrafish Individual Oligodendrocytes In Vivo. Molecular Neurobiology, 54(9), 6917-6930. doi:10.1007/s12035-016-0233-4 |
10. | Xu Y, Chen M, Hu B, Huang R and Hu B* (2017) In vivo Imaging of Mitochondrial Transport in Single-Axon Regeneration of Zebrafish Mauthner Cells. Front. Cell. Neurosci. 11:4. doi: 10.3389/fncel.2017.00004 |
11. | Huang RC, Chen M, Yang LQ, Wagle M, Guo S and Hu B* (2017) MicroRNA-133b Negatively Regulates Zebrafish Single Mauthner-Cell Axon Regeneration through Targeting tppp3 in Vivo. Front. Mol. Neurosci. 10:375. doi: 10.3389/fnmol.2017.00375 |
12. | Hu BB, Chen M, Huang RC, Huang YB, Xu Y, Yin W, Li L and Hu B* (2018) In vivo imaging of mauthner axon regeneration, remyelination and synapses re-establishment after laser axotomy in zebrafish larvae. Exp Neurol. 300:67-73. 2018. Feb. https://doi.org/10.1016/j.expneurol.2017.10.028 |
13. | Chen M, Huang RC, Yang LQ, Ren DL*, Hu B* (2019) In vivo imaging of evoked calcium responses indicates the intrinsic axonal regenerative capacity of zebrafish. FASEB J. 33(6):7721-7733. |