占 成
 | 姓 名: | 占成 |
地 址: | 安徽省合肥市黄山路443号 | |
邮 编: | 230027 | |
电 邮: | zhancheng@ustc.edu.cn |
| 教育与科研经历 |
1999.09 - 2003.07 | 华中科技大学 光电子工程系 本科 |
2003.09 - 2006.07 | 华中科技大学 生物医学工程系 硕士 |
2006.07 - 2008.09 | 北京生命科学研究所影像中心 工程师 |
2008.09 - 2011.07 | 华中科技大学 生物医学工程系 博士 |
2011.07 - 2020.12 | 北京生命科学研究所 影像中心 主任 |
2021.01 - 至今 | 中国科学技术大学生医部 特任教授 |
| 目前研究方向 |
摄食是动物和人获取能量和营养的唯一方式，吃多吃少决定了机体的健康，对体重，代谢，免疫，甚至寿命都有非常重要的影响。神经系统在摄食和代谢调控中占据主导地位。我们实验室将从神经系统如何感知机体营养状态；如何调控摄食行为；如何基于机体的营养状态调控代谢、免疫和寿命等几个方面着手，研究神经调控摄食的机制及对健康的影响。研究方向主要归纳为如下两点： |
| 代表性论文 |
1. | Jing Chen, Minxiu Cheng, Liang Wang, Lei Zhang, Dan Xu, Peng Cao, Fengchao Wang, Herbert Herzog, Sen Song, Cheng Zhan#. A vagal-NTS neural pathway that stimulates feeding. Current Biology（2020）. # corresponding author |
2. | 占成，摄食行为的神经调控。中国科学.生命科学，2020年。 |
3. | L. Mei, Y.Fan , M. Wang, X. Lv , C. Zhan#, E. Zhang#. Longitudinal in vivo recording of clock gene transcription in the brains of freely-moving mice. PNAS (2018). #co-corresponding author. |
4. | Z. Zhao, L. Wang, W. Gao, F. Hu, J. Zhang, Y. Ren, R. Lin, Q. Feng, M. Cheng, D. Ju, Q. Chi, D. Wang, S. Song, M. Luo and C. Zhan# (2017). A Central Catecholaminergic Circuit Controls Blood Glucose Levels during Stress. Neuron 95, 138-152 e135. Featured Article. # corresponding author. |
5. | D. Wang, X. He, Z. Zhao, Q.Feng, R.Lin, Y. Sun, T. Ding, F. Xu #, M. Luo #, C. Zhan # (2015) Whole-brain mapping of the direct inputs and axonal projections of POMC and AgRP neurons. Frontiers in Neuroanatomy 9:40. # co-corresponding author. |
6. | Zhan C. POMC Neurons: Feeding, Energy Metabolism, and Beyond. In Neural Regulation of Metabolism. 2018 (pp. 17-29). Springer, Singapore. |
7. | C. Zhan*#, J. Zhou *, Q. Feng, J. Zhang, S. Lin, J. Bao, P. Wu, M. Luo #, Acute and long-term suppression of feeding behavior by POMC neurons in the brainstem and hypothalamus, respectively. J Neurosci 33:3624-3632, 2013. Selected for F1000Prime. # co-corresponding author, *co-fist author,. |
8. | C. Zhan, M. Luo, Diverse patterns of odor representation by neurons in the anterior piriform cortex of awake mice. J Neurosci 30, 16662-16672, 2010. |
9. | S. Zeng, X. Lv, C. Zhan, W. R. Chen, et al. Simultaneous compensation for spatial and temporal dispersion of acousto-optical deflectors for two-dimensional scanning with a single prism. Optics Letters, 2006, 31(8): 1091-1093. |
10. | X. Lv, C. Zhan, S. Zeng, W. R. Chen, et al. Construction of multiphoton laser scanning microscope based on dual-axis acousto-optic deflector. Review of Scientific Instruments, 2006, 77(4). |
