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陶长路


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姓  名:

陶长路

地  址:

安徽省合肥市黄山路443号

邮  编:

230027

电  邮:

taocl@ustc.edu.cn

主  页:

https://faculty.ustc.edu.cn/taochanglu/zh_CN/index.htm

实  验  室:

https://neurophysics.ustc.edu.cn/main.htm




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 教育与科研经历

2026.04-至今

中国科学技术大学,特任研究员

2025.04-2026.03

中国科学技术大学,特任副研究员

2020.03-2025.03

中国科学院深圳先进技术研究院,副研究员

2017.03-2020.03

中国科学技术大学,博士后

2010.09-2017.03

中国科学技术大学,理学博士(生物物理学)

2006.09-2010.06

南方医科大学(原第一军医大学), 理学学士(生物信息学)


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 主要研究方向与研究兴趣

1.  冷冻电镜原位成像与超分辨荧光显微成像技术开发与融合

2.  大脑突触传递与可塑性的分子与细胞机制

3.  原位生物大分子结构的解析与数字化细胞构筑


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 代表性论文注:#co-1st author, *corresponding author

1.

Lv ZY#, Lu ZH#, Liu S#, Zhou P, Lau PM, Bi GQ*& Tao CL*. Vesicle3D: An Integrative Platform for 3D Segmentation and Analysis of Vesicles in Cryo-electron Tomograms. Neuroscience Bulletin (In press).

2.

Tian CL#, Qi L, Lu ZH, Liu S, Gu ML, Huang WL, Yan YT, Liu YT*, Wu J, Wang P, Zhou ZH, Bi GQ, Lau PM* & Tao CL*. Subcellular structures in native hippocampal synapses revealed by cryo-electron tomography. Neuroscience Bulletin. 2026 (Cover story)

3.

Tao CL*#, Tian CL#, Liu YT#, Lu ZH#, Qi L, Li XW, Yang LQ, Gu ML, Huang WL, Liao Z, Ma X, Wu J, Wang P, Lau PM*, Zhou ZH*, & Bi GQ*. “Kiss-shrink-run” unifies mechanisms for synaptic vesicle exocytosis and hyperfast recycling. Science. 2025, 390: eads7954.

4.

Liu YT#, Tao CL#*. Digitalizing neuronal synapses with cryo-electron tomography and correlative microscopy. Current Opinion in Neurobiology. 2022, 76 (Cover story)

5.

Liu YT#, Tao CL#, Zhang X#, Xia W, Shi DQ, Qi L, Xu C, Sun R, Li XW, Lau PM*, Zhou ZH* & Bi GQ*. Mesophasic organization of GABAA receptors in hippocampal inhibitory synapse. Nature Neuroscience. 2020, 23: 1589–1596.

6.

Liu YT#, Tao CL#, Lau PM, Zhou ZH, Bi GQ*. Postsynaptic protein organization revealed by electron microscopy. Current Opinions in Structural Biology. 2019, 54:152-160

7.

Sun R#, Liu YT#, Tao CL#*, Qi L, Lau PM, Zhou ZH, Bi GQ. An efficient protocol of cryo-correlative light and electron microscopy and its application for the study of neuronal synapses. Biophysics Reports. 2019, 5: 111 (Cover story)

8.

Tao CL#, Liu YT#, Sun R, Zhang B, Qi L, Shivakoti S, Tian CL, Zhang P, Lau PM*, Zhou ZH*, Bi GQ*. Differentiation and characterization of excitatory and inhibitory synapses by cryo-electron tomography and correlative microscopy. Journal of Neuroscience. 2018, 38(6):1493-1510. (Cover story)


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