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曾筑天


/uploads/image/2019/11/09/ab0fb6b3f5cc76f9ac924b126ce164f9.jpg 姓  名: 曾筑天
 地  址:中国科学技术大学 中校区 医学楼 307室
 邮  编:230000
 电  话:0551-63607105(办公室);0551-63603672(实验室)
 电  邮:zengzt@ustc.edu.cn




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 教育与科研经历
  2004.09 - 2008.07中国科学技术大学   学士
  2008.09 - 2014.05

中国科学技术大学   博士

  2014.08 - 2019.02加拿大卡尔加里大学  博士后
  2019.05 - 至今中国科学技术大学 生命科学与医学部 特任研究员-学术型青年杰出人才(PI)


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 目前研究方向
  1.组织驻留性免疫细胞的动态特性及功能研究;
  2.组织炎症损伤修复及再生的免疫学研究;
  3.肝脏肿瘤免疫监视及免疫浸润的可视化研究。


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 代表性论文
  1.Zeng Z, Surwarrd BG,Wong CH, Guettler C, Petri B, Burkhard R, Wyss M, Moual HL, Devinney R, Thompson GC, Blackwood J, Joffe AR, McCoy KD, Jenne CN, Kubes P. Sex-hormone-driven innate antibodies protect females and infants against EPEC infection. Nature Immunology. 2018; 19: 1100-1111.
  2.Zeng Z, Surwarrd BG,Wong CH, Geoghegan AJ, Jenne CN, Kubes P. CRIg Functions as a Macrophage Pattern Recognition Receptor to Directly Bind and Capture Blood-Borne Gram-Positive Bacteria. Cell Host&Microbe. 2016; 20 (1):99-106.
  3.Zeng Z*, Li L*, Chen Y, Wei H, Sun R, Tian Z. Interferon-gamma facilitates hepatic antiviral T cell retention for the maintenance of liver-induced systemic tolerance. Journal of Experimental Medicine. 2016; 213(6):1079-93.
  4.Zeng Z, Kong X, Li F, Wei H, Sun R, Tian Z. IL-12-based vaccination therapy reverses liver-induced systemic tolerance in a mouse model of hepatitis B virus carrier. Journal of immunology 2013, 191(8): 4184-4193.
  5.Hilscher MB, Sehrawat T, Arab Verdugo JP, Zeng Z, Gao J, Liu M, et al. Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension. Gastroenterology 2019, 157:193-209.
  6.Thanabalasuriar A, Scott BNV, Peiseler M, Willson ME, Zeng Z, Warrener P, Keller AE, et al., Neutrophil Extracellular Traps Confine Pseudomonas aeruginosa Ocular Biofilms and Restrict Brain Invasion. Cell host & microbe 2019, 25(4):526-536.
  7.Surewaard BGJ, Thanabalasuriar A, Zeng Z, Tkaczyk C, Cohen TS, Bardoel BW, et al. alpha-Toxin Induces Platelet Aggregation and Liver Injury during Staphylococcus aureus Sepsis. Cell host & microbe 2018, 24(2): 271-284 e273.


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