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江 维


/uploads/image/2019/07/22/c295f7acd9ccdc488651f47bb18847ec.png Name: Wei Jiang ( 江维)
 Address:School of Life Sciences, University of Science & Technology of China, 443 

Huangshan Road, Hefei, Anhui 230027, P.R.China
 Tel:86-551-63600125
 Fax:86-551-63600831
 E-mail:ustcjw@ustc.edu.cn




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 EDUCATION AND RESEARCH EXPERIENCE
  09/1998-06/2002B.S., Anhui University, China
  09/2002-06/2007

Ph.D, University of Science & Technology of China

  08/2007-02/2011Postdoc, Ludwig Institute for Cancer Research, Lausanne Branch, Switzerland
  03/2011-presentProfessor, University of Science & Technology of China


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 RESEARCH INTERESTS
  1.Molecular mechanisms of activation and regulation of the pattern recognition receptors (PRRs).
  2.How the gut flora controls the intestinal homeostasis, especially the role of pattern recognition receptors (PRRs) in this process.
  3.Function and development of the intestinal intraepithelial lymphocytes (IELs).


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 REPRESENTATIVE PUBLICATIONS
  1.Yan Y*, Jiang W*, Liu L, Wang X, Ding C, Tian Z, Zhou R. Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome. Cell. (In Press)
  2.Wang X*, Jiang W*, Yan Y, Gong T, Han J, Tian Z, Zhou R. RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway. Nat Immunol. 2014 ;15(12):1126-33.
  3.Jiang W, Wang X, Zeng B, Liu L, Tardivel A, Wei H, Han J, MacDonald HR, Tschopp J, Tian Z, Zhou R. Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes. J Exp Med. 2013;21;210(11):2465-76.
  4.Yan Y*, Jiang W*, Spinetti T*, Tardivel A, Castillo R, Bourquin C, Guarda G, Tian Z, Tschopp J, Zhou R. ω-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation. Immunity. 2013;27;38(6):1154-63.
  5.Jiang W, Ferrero I, Laurenti E, Trumpp A, Macdonald HR. c-Myc controls the development of CD8αα TCRαβ intestinal intraepithelial lymphocytes from thymic precursors by regulating IL-15-dependent survival. Blood. 2010;115(22):4431-8.
  6.Jiang W, Sun R, Wei H, Tian Z. Toll-like receptor 3 ligand attenuates LPS-induced liver injury by down-regulation of toll-like receptor 4 expression on macrophages. Proc. Natl. Acad. Sci. USA (PNAS) 2005;102(47): 17077–17082.
  7.Jiang W, Sun R, Zhou R, Wei H, Tian Z. TLR-9 activation aggravates concanavalin A-induced hepatitis via promoting accumulation and activation of liver CD4+ NKT cells. J Immunol. 2009;182(6):3768-74.


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