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江　维


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Name:

Wei Jiang ( 江维)

Address:

School of Basic Medical Sciences, Division  of Life Science and Medicine,

University of Science & Technology of China, 443 Huangshan Road, Hefei, Anhui 230027, P.R.China

Tel:

86-551-63600125

Fax:

86-551-63600831

E-mail:

ustcjw@ustc.edu.cn



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　EDUCATION AND RESEARCH EXPERIENCE

09/1998 - 06/2002

B.S., Anhui University, China

09/2002 - 06/2007

Ph.D, University of Science & Technology of China

08/2007 - 02/2011

Postdoc, Ludwig Institute for Cancer Research, Lausanne Branch, Switzerland

03/2011 - present

Professor, University of Science & Technology of China


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　RESEARCH INTERESTS

1.

Molecular mechanisms of activation and regulation of the pattern recognition receptors (PRRs).

2.

How the gut flora controls the intestinal homeostasis, especially the role of pattern recognition receptors (PRRs) in this process.

3.

Function and development of the intestinal intraepithelial lymphocytes (IELs).


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　REPRESENTATIVE PUBLICATIONS

1.

Commensal viruses maintain intestinal intraepithelial lymphocytes via noncanonical RIG-I signaling. Liu L, Gong T, Tao W, Lin B, Li C, Zheng X, Zhu S*, Jiang W*, Zhou R*. Nat Immunol. 2019 Dec;20(12):1681-1691.

2.

DAMP-sensing receptors in sterile inflammation and inflammatory diseases. Gong T, Liu L, Jiang W*, Zhou R*. Nat Rev Immunol. 2020 Feb;20(2):95-112.

3.

TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity. Lang X, Tang T, Jin T, Ding C*, Zhou R*, Jiang W*. J Exp Med. 2017 Feb;214(2):459-473.

4.

CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation. Tang T, Lang X, Xu C, Wang X, Gong T, Yang Y, Cui J, Bai L, Wang J, Jiang W*, Zhou R*. Nat Commun. 2017 Aug 4;8(1):202.

5.

Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome. Yan Y#, Jiang W#, Liu L, Wang X, Ding C, Tian Z*, Zhou R*. Cell. 2015 Jan 15;160(1-2):62-73.


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