![]() | Name: | Shiyong Liu(S. Y. Liu 刘世勇) |
Address: | Department of Polymer Science and Engineering, | |
University of Science and Technology of China, 230026 Hefei, P. R. China | ||
Tel: | 86-551-63607348 | |
Fax: | 86-551-63607348 | |
E-mail: | sliu@ustc.edu.cn |
EDUCATION AND RESEARCH EXPERIENCE |
1989-1993 | B.S., Wuhan University |
1993-1996 | M.S. Wuhan University |
1996-2000 | Ph.D. Fudan University |
2000-2002 | Research Fellow, University of Sussex, England |
2002-2003 | Research Associate, University of Delaware |
2004-present | Professor, University of Science and Technology of China |
RESEARCH INTERESTS |
1. | Controlled Synthesis of Polymers with Complex Architectures |
2. | Chemosensors and Biosensors for Clinical Diagnostics |
3. | Supramolecular Self-Assembly and Functional Materials |
4. | Kinetics of Chain Folding, Aggregation, and Assembly |
5. | Biomaterials, Nanomedicine, Bioimaging |
REPRESENTATIVE PUBLICATIONS |
1. | X. R. Wang, J. M. Hu, G. H. Liu, J. Tian, H. J. Wang, M. Gong, S. Y. Liu* "Reversibly Switching Bilayer Permeability and Release Modules of Photochromic Polymersomes Stabilized by Cooperative Noncovalent Interactions", J. Am. Chem. Soc. 2015, 137, 15262-15275. |
2. | G. H. Liu, G. F. Zhang, J. M. Hu, X. R. Wang, M. Q. Zhu, S. Y. Liu* "Hyperbranched Self-Immolative Polymers (hSIPs) for Programmed Payload Delivery and Ultrasensitive Detection", J. Am. Chem. Soc. 2015, 137, 11645-11655. |
3. | X. L. Hu, G. H. Liu, Y. Li, X. R. Wang, S. Y. Liu* “Cell-Penetrating Hyperbranched Polyprodrug Amphiphiles for Synergistic Reductive Milieu-Triggered Drug Release and Enhanced Magnetic Resonance Signals”J. Am. Chem. Soc. 2015, 137,362-368 (JACS Spotlights). |
4. | Y. M. Li, G. H. Liu, X. R. Wang, J. M. Hu, S. Y. Liu* "Enzyme-Responsive Polymeric Vesicles for Bacterial Strain-Selective Delivery of Antimicrobial Agents", Angew. Chem. Int. Ed. DOI: 10.1002/anie.201509401 (2015) |
5. | Y. M. Li, H. S. Yu, Y. F. Qian, J. M. Hu, S. Y. Liu*“Amphiphilic Star Copolymer-Based Bimodal Fluorogenic/Magnetic Resonance Probes for Concomitant Bacteria Detection and Inhibition” Adv. Mater. 2014, 26, 6734-6741. |
6. | X. R. Wang, J. M. Hu, G. Y. Zhang, S. Y. Liu*“Highly Selective Fluorogenic Multianalyte Biosensors Constructed via Enzyme-Catalyzed Coupling and Aggregation-Induced Emission” J. Am. Chem. Soc. 2014, 136, 9890-9893. |
7. | G. H. Liu, X. R. Wang, J. M. Hu, G. Y. Zhang, S. Y. Liu* “Self-Immolative Polymersomes for High-Efficiency Triggered Release and Programmed Enzymatic Reactions” J. Am. Chem. Soc. 2014, 136, 7492-7497. |
8. | X. R. Wang, G. H. Liu, J. M. Hu, G. Y. Zhang, S. Y. Liu* “Concurrent Block Copolymer Polymersome Stabilization and Bilayer Permeabilization via Stimuli-Regulated ‘Traceless’ Crosslinking” Angew. Chem. Int. Ed. 2014, 53, 3138-3142. |
9. | X. L. Hu, J. M. Hu*, J. Tian, Z. S. Ge, G. Y. Zhang, K. F. Luo, S. Y. Liu*"Polyprodrug Amphiphiles: Hierarchical Assemblies for Shape-Regulated Cellular Internalization, Trafficking and Drug Delivery", J. Am. Chem. Soc. 2013, 135, 17617-17629 (SciBX). |
10. | J. M. Hu, T. Wu, G. Y. Zhang, S. Y. Liu*"Efficient Synthesis of Single Gold Nanoparticle Hybrid Amphiphilic Triblock Copolymers and Their Controlled Self-Assembly",J. Am. Chem. Soc. 2012,134, 7624-7627. |
11. | G. C. Yu, C. Y. Han, Z. B. Zhang, J. Z. Chen, X. Z. Yan, B. Zhang, S. Y. Liu*, F. H. Huang* "Pillar[6]arene-Based Photo-Responsive Host-Guest Complexation", J. Am. Chem. Soc. 2012,134, 8711-8717. |
12. | C. H. Li, T. Wu, C. Y. Hong, G. Q. Zhang, S. Y. Liu*"A General Strategy to Construct Fluorogenic Probes from Charge-Generation Polymers (CGPs) and AIE-Active Fluorogens via Triggered Complexation",Angew. Chem. Int. Ed., 2012,51, 455-459. |
13. | C. H. Li, Y. X. Zhang, J. M. Hu, J. J. Cheng*, S. Y. Liu*, "Reversible Three-State Switching of Multicolor Fluorescence Emission via Multiple Stimuli-Modulated FRET Processes within Thermoresponsive Polymeric Micelles",Angew. Chem. Int. Ed., 2010,49, 5120-5124. |
14. | Z. S. Ge, Y. M. Zhou, J. Xu, H. W. Liu, D. Y. Chen*, S. Y. Liu*“High-Efficiency Preparation of Macrocyclic Diblock Copolymers via Selective Click Reaction in Micellar Media” J. Am. Chem. Soc.2009, 131, 1628-1629. |
15. | Z. S. Ge, J. M. Hu, F. H. Huang*, S. Y. Liu*“Responsive Supramolecular Gels Constructed via Crown Ether-Based Molecular Recognition” Angew. Chem. Int. Ed. 2009, 48, 1798-1802. |
16. | J. Xu, Z. Y. Zhu, S. Z. Luo, C. Wu, S. Y. Liu* “First observation of two-stage collapsing kinetics of a single synthetic polymer chain” Phys. Rev. Lett. 2006, 96, 027802. |
17. | J. M. Hu, S. Y. Liu* “Engineering Responsive Polymer Building Blocks with Host-Guest Molecular Recognition for Functional Applications” Acc. Chem. Res. 2014, 47, 2084-2095 |
18. | J. M. Hu, G. Y. Zhang, Z. S. Ge, S. Y. Liu* “Stimuli-Responsive Tertiary Amine Methacrylate-Based Block Copolymers: Synthesis, Supramolecular Self-Assembly and Functional Applications” Prog. Polym. Sci. 2014, 39, 1096-1143. |
19. | Z. S. Ge*, S. Y. Liu* “Functional Block Copolymer Assemblies Responsive to Tumor and Intracellular Microenvironments for Site-Specific Drug Delivery and Enhanced Imaging Performance” Chem. Soc. Rev. 2013, 42, 7289-7325. |
20. | J. M. Hu, G. Q. Zhang, S. Y. Liu* “Enzyme-Responsive Polymeric Assemblies, Nanoparticles and Hydrogels” Chem. Soc. Rev. 2012, 41, 5933-5949. |