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梅一德


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Name:

Yide Mei (梅一德)

Address:

School of Life Sciences

University of Science and Technology of China

443 Huangshan Road, Hefei, Anhui 230026, P.R. China

Tel/Fax:

86-551-63600921

E-mail:

meiyide@ustc.edu.cn



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　EDUCATION AND RESEARCH EXPERIENCE

1996 - 2000

B.S, School of Life Sciences, Anhui University

2002 - 2007

Ph.D, School of Life Science, University of Science and Technology of China

2007 - 2011

Postdoc Fellow, Department of Cancer Biology, School of Medicine, University of Pennsylvania

2011 - present

Professor, School of Life Sciences, University of Science and Technology of China


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　RESEARCH INTERESTS

1.

Signal transduction of oncogenes and tumor suppressors in cancer.

2.

p53-related cell signaling in tumorigenesis.

3.

Role of non-coding RNA in the regulation of tumorigenesis.


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　CURRENT RESEARCH PROJECTS

国家自然科学基金面上项目、重大研究计划培育项目、重点研发计划子课题


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　REPRESENTATIVE PUBLICATIONS

1.

Kailiang Zhao, Decai Wang, Xiaolong Zhao, Chenfeng Wang, Yongxiang Gao, Kaiyue Liu, Fang Wang, Xianning Wu, Xuejuan Wang, Linfeng Sun, Jianye Zang and Yide Mei*. WDR63 inhibits Arp2/3-dependent actin polymerization and mediates the function p53 in suppressing  metastasis. EMBO Rep (2020)

2.

Chenfeng Wang#, Yang Yang#, Guang Zhang, Jingxin Li, Xianning Wu, Xiaoling Ma, Ge Shan and Yide Mei*. Long non-coding RNA EMS connects c-Myc to cell cycle control and tumorigenesis. Proc Natl Acad Sci U S A  116: 14620-14629. (2019)

3.

Kailiang Zhao, Yang Yang, Guang Zhang, Chenfeng Wang, Decai Wang, Mian Wu* and Yide Mei*. Regulation of the Mdm2-p53 pathway by the ubiquitin E3 ligase MARCH7. EMBO Rep  19: 305-319. (2018)

4.

Yang Yang, Chenfeng Wang, Kailiang Zhao, Guang Zhang, Decai Wang and Yide Mei*. TRMP, a p53-inducible long noncoding RNA, regulates G1/S cell cycle progression by modulating IRES-dependent p27 translation. Cell Death & Dis  9: 886. (2018)

5.

Hao Gu, Qidong Li, Shan Huang, Weiguang Lu, Fangyuan Cheng, Ping Gao, Chen Wang, Lin Miao*, Yide Mei* and Mian Wu*. Mitochondrial E3 ligase March5 maintains stemness of mouse ES cells via suppression of ERK signalling. Nat Commun  6: 7112. (2015)

6.

Bing Cheng, An Xu, Mengran Qiao, Qiao Wu, Wenyu Wang*, Yide Mei* and Mian Wu*. BECN1s, a short splice variant of BECN1, functions in mitophagy. Autophagy  11: 2048-2056. (2015)

7.

Fan Yang, Huafeng Zhang, Yide Mei* and Mian Wu*. Reciprocal regulation of HIF-1α and lincRNA-p21 modulates the Warburg effect. Mol Cell  53: 88-100. (2014) (Highlighted in Science Signaling).

8.

Xingwu Wang, Meng Zha, Xiaocheng Zhao, Peng Jiang, Wenjing Du, Andrew Y.H. Tam, Yide Mei* and Mian Wu*. Siva1 inhibits p53 function by acting as an E3 ubiquitin ligase of ARF. Nat Commun 4: 1551. (2013)

9.

Xing Huang, Zhengsheng Wu, Yide Mei* and Mian Wu*. XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling. EMBO J  32: 2204-16. (2013) (Previewed in this issue).

10.

Xingwu Wang, Xiaocheng Zhao, Xiang Gao, Yide Mei* and Mian Wu*. A new role of p53 in regulating lipid metabolism. J Mol Cell Biol. 5: 147-50. (2013)

11.

Jiaxu Wang, Qianqian He, Chuanchun Han, Lei Jin, Qun Li, Yide Mei* and Mian Wu*. p53-Facilitated miR-199a-3p regulates somatic cell reprogramming. Stem Cells  30: 1405-13. (2012)

12.

Yide Mei, Jeongsik Yong, Hongtu Liu, Yigong Shi, Judy Meinkoth, Gideon Dreyfuss and Xiaolu Yang*. tRNA binds to cytochrome c and inhibits caspase activation. Mol Cell  37: 668-78. (2010) (Cover story; Previewed in this issue; Highlighted in Science Signaling and Chemical & Engineering News).


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