顾振华


/uploads/image/2019/03/12/b276255ad7576a6f53524928a2e6d4ea.jpg 姓  名: 顾振华
 地  址: 安徽省合肥市包河区金寨路96号中国科学技术大学化学系
 邮  编:230026
 电  话:+86-0551-63600069
 电  邮:zhgu@ustc.edu.cn
 主  页:http://staff.ustc.edu.cn/~zhgu/




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 教育与科研经历
  2012.1 - 至今中国科学技术大学,化学系,教授、博导
  2008.8 - 2011.12

美国加州大学圣巴巴拉分校,化学与生物学系,博士后  导师:A. Zakarian

  2007.8 - 2008.7

美国加州大学伯克利分校,化学系,博士后  导师:K. P. C. Vollhardt

  2002.9 - 2007.6

中科院上海有机化学研究所,有机化学,博士  导师:麻生明

  1998.9 - 2002.6南京大学,化学,学士   导师:吴美芳


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 目前研究方向

  我们课题组致力于过渡金属催化的有机合成反应和方法学,包括:

  1.

发展新策略高效构建C-C键,C-杂原子;

  2.

发展新的基于过渡金属催化的不对称催化反应,特别是阻旋手性等的高效构建;

  3.新催化剂的设计和开发,实现高化学和立体选择性的转化。


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 代表性论文
  1.Hypervalent Iodine‐Mediated Carbon‐Carbon Bond Cleavage and Dearomatization of 9H-Fluoren-9-ols, Ruixian Deng, Shuming Zhan, Chunyu Li and Zhenhua Gu*, Angew. Chem. Int. Ed., 2020, 59, 3093-3098. DOI:10.1002/anie.201913373.
  2.Enantioselective Carbon-Carbon Bond Cleavage for Biaryl Atropisomers Synthesis, Ruixian Deng†, Junwei Xi†, Qigang Li, Zhenhua Gu*, Chem, 2019, 5, 1834-1846. DOI:10.1016/j.chempr.2019.04.008.
  3.Enhanced Reactivity by Torsional Strain of Cyclic Diaryliodonium in Cu-Catalyzed Enantioselective Ring-Opening Reaction, Kun Zhao†, Longhui Duan†, Shibo Xu, Julong Jiang, Yao Fu*, and Zhenhua Gu* (Lead Contact), Chem, 2018, 4, p599–612.
  4.Cu-Catalyzed Enantioselective Ring Opening of Cyclic Diaryliodoniums toward the Synthesis of Chiral Diarylmethanes, Bin Li, Zengyin Chao, Chunyu Li, Zhenhua Gu*J. Am. Chem. Soc., 2018, 140 (30), pp 9400–9403. DOI:10.1021/jacs.8b05743.
  5.Palladium-Catalyzed Enantioselective Synthesis of 2-Aryl Cyclohex-2-enone Atropisomers: Platform Molecules for the Divergent Synthesis of Axially Chiral Biaryl Compounds, Chongqing Pan, Zixi Zhu, Mingkai Zhang, Zhenhua Gu*Angew. Chem. Int. Ed. 2017, 56, 4777-4781, DOI:10.1002/anie.201701467.
  6.Cleavage of the C(O)–S Bond of Thioesters by Palladium/Norbornene/Copper Cooperative Catalysis: An Efficient Synthesis of 2-(Arylthio)aryl Ketones, Fenggang Sun, Miao Li, Congfa He, Bin Wang, Bin Li, Xianwei Sui, Zhenhua Gu*J. Am. Chem. Soc., 2016, 138 (24), pp 7456–7459, DOI:10.1002/anie.201509571.
  7.Enantioselective Synthesis of Atropisomeric Vinyl Arene Compounds by Palladium Catalysis: A Carbene Strategy, Jia Feng†, Bin Li†, Yun He, Zhenhua Gu*Angew. Chem. Int. Ed. 2016, 55, 2186 –2190, DOI:10.1002/anie.201509571.
  8.Palladium-Catalyzed Catellani ortho-Acylation Reaction: An Efficient and Regiospecific Synthesis of Diaryl Ketones, Yunze Huang, Rui Zhu, Kun Zhao, Zhenhua Gu*Angew. Chem., Int. Ed. 2015, 54, 12669-12672 DOI:10.1002/anie.201506446.
  9.Palladium-Catalyzed Intramolecular Asymmetric C-H Functionalization/Cyclization Reaction of Metallocenes: An Efficient Approach toward the Synthesis of Planar Chiral Metallocene Compounds, Ruixian Deng,† Yunze Huang,† Xinna Ma, Gencheng Li, Rui Zhu, Bin Wang, Yan-Biao Kang,* and Zhenhua Gu*J. Am. Chem. Soc. 2014, 136, 4472-4475, DOI: 10.1021/ja500699x. (R. D. and Y. H. contributed equally)
  10.Pd-Catalyzed Chemoselective Catellani Ortho-Arylation of Iodopyrroles: Rapid Total Synthesis of Rhazinal, Xianwei Sui, Rui Zhu, Gencheng Li, Xinna Ma, and Zhenhua Gu*J. Am. Chem. Soc. 2013, 135, 9318-9321, DOI: 10.1021/ja404494u.


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