顾振华
 | 姓 名: | 顾振华 |
地 址: | 安徽省合肥市包河区金寨路96号中国科学技术大学化学系 | |
邮 编: | 230026 | |
电 话: | +86-0551-63600069 | |
电 邮: | zhgu@ustc.edu.cn | |
主 页: | http://staff.ustc.edu.cn/~zhgu/ |
| 教育与科研经历 |
2012.1 - 至今 | 中国科学技术大学，化学系，教授、博导 |
2008.8 - 2011.12 | 美国加州大学圣巴巴拉分校，化学与生物学系，博士后 导师：A. Zakarian |
2007.8 - 2008.7 | 美国加州大学伯克利分校，化学系，博士后 导师：K. P. C. Vollhardt |
2002.9 - 2007.6 | 中科院上海有机化学研究所，有机化学，博士 导师：麻生明 |
1998.9 - 2002.6 | 南京大学，化学，学士 导师：吴美芳 |
| 目前研究方向 |
我们课题组致力于过渡金属催化的有机合成反应和方法学，包括： | |
1. | 发展新策略高效构建C-C键，C-杂原子； |
2. | 发展新的基于过渡金属催化的不对称催化反应，特别是阻旋手性等的高效构建； |
3. | 新催化剂的设计和开发，实现高化学和立体选择性的转化。 |
| 代表性论文 |
1. | Hypervalent Iodine‐Mediated Carbon‐Carbon Bond Cleavage and Dearomatization of 9H-Fluoren-9-ols, Ruixian Deng, Shuming Zhan, Chunyu Li and Zhenhua Gu*, Angew. Chem. Int. Ed., 2020, 59, 3093-3098. DOI:10.1002/anie.201913373. |
2. | Enantioselective Carbon-Carbon Bond Cleavage for Biaryl Atropisomers Synthesis, Ruixian Deng†, Junwei Xi†, Qigang Li, Zhenhua Gu*, Chem, 2019, 5, 1834-1846. DOI:10.1016/j.chempr.2019.04.008. |
3. | Enhanced Reactivity by Torsional Strain of Cyclic Diaryliodonium in Cu-Catalyzed Enantioselective Ring-Opening Reaction, Kun Zhao†, Longhui Duan†, Shibo Xu, Julong Jiang, Yao Fu*, and Zhenhua Gu* (Lead Contact), Chem, 2018, 4, p599–612. |
4. | Cu-Catalyzed Enantioselective Ring Opening of Cyclic Diaryliodoniums toward the Synthesis of Chiral Diarylmethanes, Bin Li, Zengyin Chao, Chunyu Li, Zhenhua Gu*, J. Am. Chem. Soc., 2018, 140 (30), pp 9400–9403. DOI:10.1021/jacs.8b05743. |
5. | Palladium-Catalyzed Enantioselective Synthesis of 2-Aryl Cyclohex-2-enone Atropisomers: Platform Molecules for the Divergent Synthesis of Axially Chiral Biaryl Compounds, Chongqing Pan, Zixi Zhu, Mingkai Zhang, Zhenhua Gu*, Angew. Chem. Int. Ed. 2017, 56, 4777-4781, DOI:10.1002/anie.201701467. |
6. | Cleavage of the C(O)–S Bond of Thioesters by Palladium/Norbornene/Copper Cooperative Catalysis: An Efficient Synthesis of 2-(Arylthio)aryl Ketones, Fenggang Sun, Miao Li, Congfa He, Bin Wang, Bin Li, Xianwei Sui, Zhenhua Gu*, J. Am. Chem. Soc., 2016, 138 (24), pp 7456–7459, DOI:10.1002/anie.201509571. |
7. | Enantioselective Synthesis of Atropisomeric Vinyl Arene Compounds by Palladium Catalysis: A Carbene Strategy, Jia Feng†, Bin Li†, Yun He, Zhenhua Gu*, Angew. Chem. Int. Ed. 2016, 55, 2186 –2190, DOI:10.1002/anie.201509571. |
8. | Palladium-Catalyzed Catellani ortho-Acylation Reaction: An Efficient and Regiospecific Synthesis of Diaryl Ketones, Yunze Huang, Rui Zhu, Kun Zhao, Zhenhua Gu*, Angew. Chem., Int. Ed. 2015, 54, 12669-12672 DOI:10.1002/anie.201506446. |
9. | Palladium-Catalyzed Intramolecular Asymmetric C-H Functionalization/Cyclization Reaction of Metallocenes: An Efficient Approach toward the Synthesis of Planar Chiral Metallocene Compounds, Ruixian Deng,† Yunze Huang,† Xinna Ma, Gencheng Li, Rui Zhu, Bin Wang, Yan-Biao Kang,* and Zhenhua Gu*, J. Am. Chem. Soc. 2014, 136, 4472-4475, DOI: 10.1021/ja500699x. (R. D. and Y. H. contributed equally) |
10. | Pd-Catalyzed Chemoselective Catellani Ortho-Arylation of Iodopyrroles: Rapid Total Synthesis of Rhazinal, Xianwei Sui, Rui Zhu, Gencheng Li, Xinna Ma, and Zhenhua Gu*, J. Am. Chem. Soc. 2013, 135, 9318-9321, DOI: 10.1021/ja404494u. |
