| 报告题目 | Biomimetic Block Copolymer Vesicles: towards Smart Nanomedicines |
| 报告人 | Prof. Sébastien Lecommandoux |
| 报告人单位 | Université de Bordeaux, France |
| 报告时间 | 2012-09-16 |
| 报告地点 | 合肥微尺度物质科学国家实验室一楼科技展厅 |
| 主办单位 | 合肥微尺度物质科学国家实验室,中科院软物质化学重点实验室 |
| 报告介绍 | We will report an overview on the self-assembly in water of amphiphilic block copolymers into polymersomes, and their applications in loading and controlled release of both hydrophilic and hydrophobic molecules and biomolecules. We will pay special attention to polysaccharide and polypeptide-based block copolymer vesicles that we have studied these recent years in our group. These newly developed copolymers that mimic the structure and function of glycoproteins represent an example of the effectiveness of a biomimetic strategy in implementing materials design. In addition, magnetic polymersomes, including iron oxide γ-Fe2O3 nanoparticles are currently investigated, together with their potential applications as contrast agent for diagnosis and as therapeutic nanoparticles using hyperthermia. Exciting and very promising results about their therapeutic evaluation for tumor targeting and in vivo tumor regression studies will be presented. Finally our recent advances in using “biomimicry approaches” to design complex, compartmentalized materials will be proposed.
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